The mechanical properties of the poly (vinyl chloride) (PVC) and poly (glycidyl methacrylate) [poly (GMA)] blend system and the PVC and poly (hydroxyethyl methacrylate) [poly (HEMA)] blend system and their crosslinked films were investigated. At the same time, the mechanical properties for the corresponding graft copolymers such as PVC-g-GMA, PVC-g-HEMA, and their crosslinked films were also investigated in this study. The results showed that the tensile strengths for PVC-poly (GMA) blend systems were higher than those for PVC-g-GMA graft copolymer, and the tensile strengths for PVC-g-HEMA were higher than those for PVC-poly (HEMA) blend systems. However, the mechanical properties for the PVC-poly (GMA) blend system were not affected by the crosslinking of the blend system, but those for PVC-poly (HEMA) and their graft copolymers decreased with an increase of the equivalent ratio ([NCO]/[OH]) of the crosslinker. Finally, the surface hydrophilicity of the PVC-g-HEMA graft copolymer and PVC-poly (HEMA) blends were also assessed through measuring the contact angle.