Microlayers of polycarbonate (PC) with poly(methylmethacrylate) (PMMA) or poly(styrene-co;acrylonitrile) (SAN) were processed with varying layer thicknesses. Adhesion between PC and PMMA was found to be an order of magnitude higher than between PC and SAN, as determined with the T-peel method. To probe the effect of the adhesion difference on yielding and deformation of PC/PMMA and PC/SAN microlayers, the macroscopic stress-strain behavior was examined as a function of layer thickness and strain rate, and the results were interpreted in terms of the microdeformation behavior. During yielding, crazes in thick SAN layers opened up into cracks; however, PC layers drew easily because local delamination relieved constraint at the PC/SAN interface. Adhesion of PC/PMMA was too strong for delamination at the interface when PMMA crazes opened up into cracks at low strain rates. Instead, PMMA cracks tore into neighboring PC layers and initiated fracture. At higher strain rates, good adhesion produced yielding of thick PMMA layers, a phenomenon not observed with thick SAN layers. The change in microdeformation mechanism of PMMA with increasing strain rate produced a transition in the yield stress of PC/PMMA microlayers. Microlayers of both PC/SAN and PC/PMMA with thinner layers (individual layers 0.3-0.6 mu m thick) exhibited improved ballistic performance compared to microlayers with thicker layers (individual layers 10-20 mu m thick), which was due to cooperative yielding of both components.