At the present time, thermal insulation is almost not used in fabric of tall residential buildings in Hong Kong, as their fabric Slabs usually comprise concrete layer covered on each side by plaster layers. This study investigates into the influence of an existence of the thermal insulation layer in the outside walls on the yearly cooling load and yearly maximum cooling demand in two typical residential flats in a high-rise residential building by employing HTB2, detailed building heat transfer simulation software. During the investigations, the thermal insulation layer up to 15 cm thick was placed either at the inside, or at the outside, or at the middle part of the outside wall structure. Then, the concrete layer was up to 40 cm thick. The simulation predictions indicate that the highest decrease in the yearly cooling load of up to 6.8% is obtained when a 5 cm thick thermal insulation layer faces the inside of the residential flat. The highest decrease in the yearly maximum cooling demand of 7.3% is recorded when a 5 cm thermal insulation layer faces either the outside or the inside of the flat; this depends on the flat orientation. However, much weaker reductions in the yearly cooling load and yearly maximum cooling demand are found when the thickness of thermal insulation is increased above 5 cm and the thickness of concrete is increased above 10 cm.