화학공학소재연구정보센터
Journal of the American Chemical Society, Vol.119, No.50, 12031-12040, 1997
Total synthesis of (+/-)-scopadulcic acid B
The first total synthesis of a scopadulan diterpene is described. The key step is a double Heck cyclization of dienyl aryl iodide 8 to form tetracyclic enones 24 and 25 in 80-85% combined yield.