The present theoretical analysis demonstrates that the membrane surface potential effect of a uniformly charged artificial membrane can be substituted by an electrical resistance term which balances the passive membrane resistance term. Depending on the sign of this electrical resistance term, the global membrane resistance for a charged solute may be either enhanced or lowered as compared to the passive membrane resistance term. By itself, such a membrane charge effect cannot lead to active transport phenomena. However, the combined effects between two opposite enzymic reactions acting on both parts of a uniformly charged porous membrane and in unstirred layers with the membrane surface potentials lead to the concept of biomimetic membranes able to specifically transport a molecule against its chemical gradient.