The influence of some structural parameters on wall slip phenomena during the flow of oil-in-water model emulsions has been investigated using geometries with smooth and rough surfaces. A wall slip phenomenon has been quantified as the relative difference between the areas under the flow curves obtained using geometries with both types of surfaces. Experimental results demonstrate that wall slip effects phenomena vanish as the disperse phase fraction, the emulsifier content, or the agitation speed applied during the emulsification process increase. These influences have been related to changes in both droplet size and interparticle interactions. In addition to this, the shear stress range in which wall slip is more important coincides with the region at which a shear-induced deflocculation process occurs. In this region, low reproducible values of the flow curve were obtained by using geometries with smooth surfaces.