The Flory theory has been applied to the following binary mixtures: 2-methoxyethanol (2ME) + 2-ethoxyethanol (2EE), or + 2-butoxyethanol (2BE), and + 2-(2-methoxyethoxy)ethanol (22MEE), $2-(2-ethoxyethoxy)ethanol (22EEE), or + 2-(2-buthoxyethoxy)ethanol (22BEE). For pure compounds, the coefficients of thermal expansion cc and jsothermal compressibility K-T were estimated in order to compute the Flory characteristic parameters, pressure p(i)* and volume v(i) *. For each mixture, the energetic parameter chi (12) was fitted to excess enthalpy data H-E at 298.15 K and used to predict correctly the corresponding excess volume VE. The variation of chi (12) versus the numberof C atoms + -O- groups in alkoxyethanols is similar to that found previously for 1-alkanol $ 1-alkanol mixtures.