We studied the physical properties of three series of new fluorinated liquid crystal components and prepared some mixtures by using these components. Decahydronaphthalenes have low Deltan with relatively high T-NI. Naphthalenes and Tetrahydronaphthalenes have large Delta epsilon and variety range of Deltan (0.08-0.21). Moreover, we have revealed that the fluoro- substituent at C-1 position for the naphthalene and the tetrahydronaphthalene ring has effects to increase T-NI and to reduce gamma (1) with good solubility. Then, we have designed some LC mixtures for AM-LCD having good performance with 4V-driving, quick response, high birefringence. low birefringence, wide temperature range and low driving voltage.