Cellulose nitrate membranes were embedded with two different commercially available liquid crystals and the transport of a model drug through the membranes was examined spectrophotometrically. It was found that upon changing the temperature of the system, membranes without liquid crystal showed no temperature dependent drug transport properties. Membranes embedded with liquid crystal however, showed a distinct temperature variation in the drug release. It was found that the rate of drug transport was dependent on the amount of liquid crystal deposited on the membrane and by cycling the temperature of the system, pulsatile drug release could be achieved.