Complete oxidation of solvents (e.g., acetone, butyl acetate and isopropanol) over base metal oxides was investigated using a fixed bed reactor. Mixed oxides with perovskite (e.g. LaMnO3) or spinel structure (e.g. CuMn2O4) have been prepared and characterized by BET surface area measurements and X-ray diffraction. The influence of catalyst type and composition, reaction temperature and feed composition on the formation of CO2 and partially oxidized intermediates has been examined.