Experiments for subcooled water flow and for steam-water two-phase flow were conducted to investigate the effects of pulsation upon transient heat transfer characteristics in a closed-circulation helical-coiled tube steam generator. The non-uniform property of local heat transfer with steady flow was examined. The secondary flow and the effect of interaction between the flow oscillation and secondary flow were analyzed on basis of the experimental data. Some new phenomena were observed and explained. Correlations were proposed for average and local heat transfer coefficients both under steady and oscillatory flow conditions. The results showed that there exist considerable variations in local and peripherally time-averaged Nusselt numbers for pulsating flow. Investigations of pressure drop type oscillations and their thresholds for steam-water two-phase flow in a uniformly heated helical tube were also reported.