Graph theoretical indices were exclusively used in the prediction of indices of refraction, n, and glass transition temperatures, T-g, into a group of addition polymers. Models with 10 variables were selected for the prediction of n (r = 0.981, SEE = 0.0147) and T-g/M (r = 0.946, SEE = 0.439). The average errors in the predictions were 0.69% and 12.7% for n and T-g, respectively. The descriptors involved in these models were calculated from the structures of the monomers.