Journal of Bioscience and Bioengineering, Vol.90, No.3, 338-340, 2000
Addition of reducing agent dithiothreitol improves 4-decanolide synthesis by the genus Sporidiobolus
Two species of the genus Sporidiobolus, S. johnsonii and S. ruinenii, were used to study the effect of the reducing agent, dithiothreitol (DTT), on 4-decanolide production using ricinoleic acid as the substrate. The results indicate that the addition of DTT into the cultures significantly enhanced 4-decanolide biosynthesis by the two species.