The electrooxidation of some low molecular weight alcohols, such as ethanol, ethylene glycol and n-propanol, is discussed in terms of reaction mechanisms and catalytic activity of the anode material. Some examples of a single cell, using a proton exchange membrane (PEM) as electrolyte, are given to illustrate interesting results, particularly for the direct electrooxidation of ethanol. This alcohol may replace methanol in a direct alcohol fuel cell.