염화페나실로 합성된 새로운 4급 암모늄염의 계면 활성도

배선건; 연영흠; Sun Kun Bae; Young Heum Yeon

Journal of the Korean Industrial and Engineering Chemistry, Vol.13, No.5, 486-489, August, 2002

Export Citation

염화페나실로 합성된 새로운 4급 암모늄염의 계면 활성도

Surface Activity of New Quaternary Ammonium Salts Prepared from Phenacyl Chloride

배선건^†, 연영흠

군산대학교 과학기술학부, 군산 573-701

Sun Kun Bae^†, and Young Heum Yeon

School of Science and Technology, Kunsan National University, Kunsan 573-701, Korea

E-mail:

초록

염화페나실과 N,N-dimethylalkylamine들의 반응으로 새로운 일련의 4급 암모늄염[dimethyl-(2-oxo-2-phenethyl)alkylammonium chlorides (DPAACs: 3]을 합성하였다. 이들의 구조와 물리적 특성을 조사하였고, 몇 가지 계면활성제의 특성을 측정하였다. 4급 암모늄염 3의 표면장력(γcmc)과 최소저해농도(MIC)는 알킬기의 탄소수에 영향을 받은 것으로 나타났으며, 특히 알킬기의 탄소수가 12개인 화합물 3c가 가장 높은 살균력과 좋은 계면활성을 보였다.

A new series of quaternary ammonium salts, [dimethyl-(2-oxo-2-phenethyl)alkylammonium chlorides (DPAACs): 3] were prepared from the reaction of phenacyl chloride with N,N-dimethylalkylamines in boiling ethanol or isopropanol. The structure and the physical properties of these compounds were investigated and some surfactant properties of them were measured. The surface tension (γcmc) and the minimal inhibitory concentration (MIC) of quaternary ammonium salts were found to be influenced by the carbon atom of alkyl group and especially, compound 3c of 12 carbon atom of alkyl group exhibited high bactericidal activity and good surface-active properties.

Keywords:phenacyl chloride;quaternary ammonium;surfactant;minimal inhibitory

[References]

U.S. Patent, 2,108,765 (1938)
Quack JM, Cosmetics Toiletries, 91, 35 (1976)
Mccarthy JP, Mores LR, Schlossman ML, J. Soc. Cosmet. Chem., 27, 559 (1976)
Schaeufele PJ, J. Am. Oil Chem. Soc., 61, 387 (1984)
Magdassi S, Shani A, J. Am. Oil Chem. Soc., 67, 605 (1990)
Baydar A, Johnston R, Int. J. Cosmetic Sci., 13, 169 (1991)
Polovsky SB, Cosmet. Toiletries, 106, 59 (1991)
Ohta S, Makino M, Nagai K, Zenda H, Biol. Pharm. Bull., 19, 308 (1996)
Suhara T, Shimano F, Sato Y, Fukui H, Colloids Surf., 119, 105 (1996)
Esumi K, Toyoda A, Goino M, Suhara T, Fukui H, Koide Y, J. Colloid Interface Sci., 202(2), 377 (1998)
Kim TS, Kida T, Nakatsuji Y, Ikeda I, Langmuir, 12(26), 6304 (1996)
Kim TS, Ha JW, Kim DI, Rang MJ, Ahn HJ, J. Jpn. Oil Chem. Soc., 49, 15 (2000)
한상섭, "페나실디메칠 알킬염화 암모늄염의 랫드를 이용한 급성경구독성시험," (시험번호: G01078), 한국화학연구원 안정성연구센터 (2001)

[Referenced By]

[1] U.S. Patent, 2,108,765 (1938)

[2] Quack JM, Cosmetics Toiletries, 91, 35 (1976)

[3] Mccarthy JP, Mores LR, Schlossman ML, J. Soc. Cosmet. Chem., 27, 559 (1976)

[4] Schaeufele PJ, J. Am. Oil Chem. Soc., 61, 387 (1984)

[5] Magdassi S, Shani A, J. Am. Oil Chem. Soc., 67, 605 (1990)

[6] Baydar A, Johnston R, Int. J. Cosmetic Sci., 13, 169 (1991)

[7] Polovsky SB, Cosmet. Toiletries, 106, 59 (1991)

[8] Ohta S, Makino M, Nagai K, Zenda H, Biol. Pharm. Bull., 19, 308 (1996)

[9] Suhara T, Shimano F, Sato Y, Fukui H, Colloids Surf., 119, 105 (1996)

[10] Esumi K, Toyoda A, Goino M, Suhara T, Fukui H, Koide Y, J. Colloid Interface Sci., 202(2), 377 (1998)

[11] Kim TS, Kida T, Nakatsuji Y, Ikeda I, Langmuir, 12(26), 6304 (1996)

[12] Kim TS, Ha JW, Kim DI, Rang MJ, Ahn HJ, J. Jpn. Oil Chem. Soc., 49, 15 (2000)

[13] 한상섭, "페나실디메칠 알킬염화 암모늄염의 랫드를 이용한 급성경구독성시험," (시험번호: G01078), 한국화학연구원 안정성연구센터 (2001)