There is considerable interest in producing fibres that mimic the impressive tensile properties of spider drag line silk. It must, however, be recognised that these properties have been assessed largely on the basis of their average values; there can be significant variability about these averages. The natural variability can also serve as a useful indicator of the range of values over which particular properties of biomimetic silk may be tailored. Here we quantify several tensile properties of drag line from Argiope trifasciata spiders. We distinguish between two groups of properties on the basis of their statistical coefficient of variation. There is significantly greater scope for tailoring the viscoplastic hardening aspects of drag line, compared to the variability of the initial elastic response or the yield strength. We also consider whether elastic modulus, yield strength and viscoplastic hardening can be controlled independently of one another.