In spiral-wound membrane modules, spacers are used to enhance wall shear stress and to promote eddy mixing, thereby reducing wall concentration and fouling. Insights into the effect of spacer filaments on flow patterns in narrow channels were obtained using a computational fluid dynamics (CFD) code. The flow patterns were visualized for different filament configurations incorporating variations in mesh length, filament diameter and for channel Reynolds numbers up to 1000. The simulated flow patterns revealed the dependence of the formation of recirculation regions on the filament configuration, mesh length, filament diameter and the Reynolds number. When the channel Reynolds number is increased above 300, the flow becomes super-critical showing time-dependent movements for a filament located in the center of a narrow channel; and when the channel Reynolds number is increased above 500, the flow becomes super-critical for a filament adjacent to the membrane wall. For multiple filament configurations, flow transition can occur at channel Reynolds numbers as low as 80 for the submerged spacer at a very small mesh length (l(m)/h(ch) = 1) and at a slightly larger Reynolds number at a larger mesh length (l(m)/h(ch) = 4). The transition occurs above Re-ch of 300 for the cavity spacer (l(m)/h(ch) = 4) and above Re-ch of 400 for the zigzag spacer (l(m)/h(ch) = 4).