As operators seek novel ways to minimize costs while maximizing revenues, the concept of using coiled tubing-deployed through-tubing inflatable packers in a straddle configuration is being pursued as a viable and economical alternative to a complete workover to prolong the life of a well. While a workover may offer the most complete solution to the problem in hand, a straddle option may be chosen as the way forward for a number of reasons, among them logistics, equipment, time, matrix damage, and cost. The most common application for straddle systems is to isolate a section of the wellbore while preserving wellbore accessibility below the isolated section. For example, a straddle system can isolate an upper or intermediate zone for injection or production. A straddle option can isolate a damaged section of the wellbore or straddle a malfunctioning production packer. Straddle systems can also function as sealed velocity strings or be used to remedially install either flow control devices or sand control screens. Regardless of the reason, once a straddle option is selected, the choice of running an inflatable system will in all probability be based on the geometry of the wellbore. It would be very unlikely, for example, to select an inflatable system when a mechanical solution could be used.