Biotechnology Letters, Vol.24, No.23, 1967-1970, 2002
Asperenone: an inhibitor of 15-lipoxygenase and of human platelet aggregation from Aspergillus niger
Asperenone was isolated from the fermented broth of Aspergillus niger CFTRI 1105 and acted as an inhibitor of soybean 15-lipoxygenase (15-LOX) and human platelet aggregation. The IC50 values against 15-LOX and human platelet aggregation were 0.3 mM and 0.23 mM, respectively.