Microbubble technology is now gathering much interest in industrial fields for its excellent gas-dissolving ability. This study was the first trial in using microbubbles in hydrate formation, and it has been demonstrated that a microbubble system is a promising method for hydrate formation for two reasons: (1) its excellent gas-dissolution ability and (2) its ability to make the conditions of hydrate nucleation more mild due to the microbubbles' property of increasing interior gas pressure while decreasing in size under water.