Excess molar enthalpies (H-E) of binary mixtures of N,N-dimethylacetamide with ethylbenzene, chlorobenzene, bromobenzene, nitrobenzene, aniline and acetophenone have been measured with a Parr 1451 calorimeter at 298.15 K, over the entire range of composition. The experimental values of H-E are positive in the mixture of N,N-dimethylacetamide with ethylbenzene. The other experimental values of H-E are negative. The results are discussed with regard to the associating abilities of the components.