The cathodes with various binders such as carboxymethyl cellulose (CMC), polyvinyl alcohol (PVA), polytetrafluoroethylene (PTFE), and polyethylene oxide (PEO), in different combinations including sole component in the case of PEO, were prepared. These cathodes were examined by morphology measurement, electrochemical characteristics, and discharge performance to inspect the effect of binder on Li-S battery. The morphology of cathode varies with various binder combination and the performance of battery is greatly affected by the morphology. The specific surface area (SSA) of cathode composite material increases and the interface resistance reduces with increasing content of PTFE introduced into the cathode. The battery with cathode including PTFE (15 wt%) showed the distinguished power enhancement, compared with those composed of other binder combinations. The cathode with predominant results was able to increase SSA and sulfur utilization by 16 m²/g and more than 70%, respectively.