Oxidation of methanol at a Pt-Ru/Ti mini-mesh anode has been investigated. The oxidation is efficient giving low anode potential, e.g. 520 mV versus RHE at a Current density of 200 mA cm(-2). The potentials were lower than that obtained at catalysed carbon cloth anode and at catalysed Teflon-bonded gas diffusion anode, under similar conditions. An outstanding performance was demonstrated by subjecting the electrolytic cell, including the electrolytes, to centrifugal force to enhance mass transfer and to accelerate gas bubble disengagement from the electrode surfaces, the electrolytes and the membrane. The acceleration field caused a significant reduction in the anode potential (up to 500 mV at 300 mA cm(-2)), compared with a static cell, and increased current density greatly by up to 250 mA cm(-2) at 500 mV versus RHE, at a relative acceleration rate of 190 and at 80 degreesC. Increasing the methanol concentration and the electrolyte temperature increased the rate of methanol oxidation. An increase in the concentration of the electrolyte led to a reduction in the cell resistance. These improvements in anode potential were improved further in a centrifugal field, compared to a gravitational field. (C) 2003 Elsevier Science B.V. All rights reserved.