Experimental solubilities were determined for 1,1,1,2-tetrafluoroethane (HFC134a) in triethylene glycol dimethyl ether and in tetraethylene glycol dimethyl ether at 101.33 kPa refrigerant partial pressure in the low-temperature range (258.15-298.15 K). The experimental device was adapted from an apparatus commonly used to measure slightly soluble gases. Because HFC134a was highly soluble in the two polyglycols, the mole fraction of the refrigerant was calculated by the phi-gamma method and the symmetrical criteria for the components. The solubilities of the refrigerant in the two solvents were very similar. The thermodynamic quantities related to the solution process were also obtained from the solubility data. The isobaric solubilities predicted by the original and Dortmund UNIFAC versions were compared with the experimental values to test the interaction parameters of Kleiber (Fluid Phase Equilib. 1995, 107, 161) and Kleiber and Axmann (Comput. Chem. Eng. 1998, 23, 63).