The hydrothermal reaction between Cd(NO3)(2), trimesic acid (H3BTC), 1,2-bis(4-pyridyl)ethane (BPE), and triethylamine under mild conditions yielded, after 3 days, a novel three-dimensional metal-organic framework, [Cd-1.5(BTC)(BPE)(H2O)(2)].(H2O), which has been characterized structurally using single-crystal and powder X-ray diffraction, elemental analysis, infrared and Raman spectroscopies, thermogravimetry, and differential scanning calorimetry. The structure exhibits a 2-fold interpenetration of identical [Cd-1.5(BTC)(BPE)(H2O)(2)] single frameworks, described as an unusual (9,3 4) net. Crystal data: Cd1.5C21H21N2O9, monoclinic, space group C2/c, with a = 10.8264(5) Angstrom, b = 17.4563(5) Angstrom, c = 24,2605(11) Angstrom, beta = 91.978(2)degrees, V = 4582.2(3) Angstrom(3), and Z = 8.