Femtosecond time-resolved photoelectron imaging was applied to (1+2') resonance-enhanced multiphoton ionization of deuterated pyrazine. The resonances with the 3s and 3p Rydberg states and rotational dephasing on a picosecond time-scale were observed similarly with pyrazine-H4. The photoionization dynamics of pyrazine-D4 was found to be identical to that of H4 at the photoionization wavelength of 393 nm. No signature was observed of the influence of the superexcited states upon ionization.