Ti-doped nonporous silica was used as a support to prepare nanometer gold catalysts by the deposition-precipitation method for the direct vapor-phase epoxidation of propylene with O-2 and H-2. Both the catalysts dried under vacuum at room temperature and the catalysts calcined at 573 K in air exhibited catalytic activity to form PO even at a temperature as low as 323 K. The calcined catalysts were more stable and more active at higher temperatures than the dried catalysts. Simple filtration after aging the suspension resulted in the catalysts more active and selective but less stable than the complete washing of the solid precursors. Pretreatment in argon appreciably increased the catalytic activity and H2 efficiency over the An catalysts deposited on Ti-doped nonporous silica, which was opposite to the case of Au/Ti-MCM catalysts. Similar deactivation rate of An catalysts supported on a variety of titania-silica supports with different porosities suggests that quick deactivation of An catalysts within hours is mainly affected by the surface properties rather than the pore structure and diffusion limitation of the supports. (C) 2003 Elsevier B.V. All rights reserved.