A new class of Lyapunov uniformly globally asymptotically stable (UGAS) protocols in networked control systems (NCS) is considered. It is shown that if the controller is designed without taking into account the network so that it yields input-to-state stability (ISS) with respect to external disturbances (not necessarily with respect to the error that will come from the network implementation), then the same controller will achieve semi-global practical ISS for the NCS when implemented via the network with a Lyapunov UGAS protocol. Moreover, the ISS gain is preserved. The adjustable parameter with respect to which semi-global practical ISS is achieved is the maximal allowable transfer interval (MATI) between transmission times. (C) 2004 Elsevier Ltd. All rights reserved.