Journal of Bioscience and Bioengineering, Vol.98, No.3, 182-186, 2004
Effects of static magnetic field on growth of leptospire, Leptospira interrogans serovar canicola: Immunoreactivity and cell division
The effects of the exposure of the bacterium, Leptospira interrogans serovar canicola to a constant magnetic field with magnetic flux density from a permanent ferrite magnet=140+/-5 mT were studied. Changes in Leptospira cells after their exposure to the field were determined on the basis of changes in their growth behavior and agglutination immuno reactivity with a homologous antiserum using dark-field microscopy together with visual imaging. The data showed that the exposed Leptospira cells have lower densities and lower agglutination immunoreactivity than the unexposed control group. Interestingly, some of the exposed Leptospira cells showed abnormal morphologies such as large lengths. We discussed some of the possible reasons for these observations.
Keywords:leptospirosis;Leptospira interrogans;magnetic field;dark-field microscopy;immunoreactivity;cell division