Porous scaffolds made of n-HA/PA66 composite were fabricated through porogen-leaching technique. The structure, phase and morphology of the scaffolds were investigated by using IR, XRD and SEM, and the physical properties were also studied. The results indicated that the two phases in the composite dispersed uniformly and chemical bonding existed between the two phases. The porosity was proportional to the content of the porogen, and macropores and micropores coexisted and interconnected in the scaffolds. When the porosity was up to 80%, the porosity and the mechanical strength of the scaffolds prepared can meet the demands of tissue engineering simultaneously. (C) 2005 Springer Science + Business Media, Inc.