Single crystalline PbMoO4 dendrites were prepared by a simple hydrothermal method in the presence of surfactants. The formation and evolution of these dendrites was investigated by transmission electron microscopy, and the results clearly showed that the dendritic structure was achieved through oriented attachment of nanoparticles along crystallographically specific direction while the traditional Ostwald ripening mechanism also acted to form the initial particles before attachment and smooth the morphology of the dendrites after attachment.