Journal of Bioscience and Bioengineering, Vol.99, No.1, 72-74, 2005
Time-course data analysis of gene expression profiles reveals purR regulon concerns in organic solvent tolerance in Escherichia coli
A time-course gene-expression profile was generated for Escherichia coli TK31 when it was exposed to an organic solvent mixture, and classified by fuzzy adaptive resonance theory (Fuzzy ART). It was found that the purR regulon plays an important role in the organic solvent tolerance (OST) of E. coli.
Keywords:Escherichia coli;organic solvent tolerance;mar-sox regulon;DNA microarray;fuzzy adaptive;resonance theory (Fuzzy ART);purR regulon