Development of a new processing method for the effective use of rice-Shochu distillation remnants is an important subject for the reduction of environmental pollution. In this study, inhibitory effects on the growth of human stomach tumor cells along with the induction of apoptosis were obtained for powder treated with ethanol from freeze-dried supernatant of rice-Shochu distillation remnants in vitro. Futhermore, the powder obtained from rice-Shochu distillation remnants showed no toxicity to normal rats in vivo experiments. These results suggest that rice-Shochu distillation remnants might be effectively used not only as medicine but also as food supplements for health.