The paper presents a detailed simulation of a V-shaped micro heat pipe. The effect of the substrate temperature on the model has been considered. A new method for calculating dry-out length has been proposed. The sensitivity of the model to variations in thermophysical properties and design parameters has been studied. The variations in the contact angle for the substrate-coolant liquid system, surface tension and viscosity of the coolant liquid, inclination, groove angle, length of adiabatic section and radius of ungrooved substrate have been considered. The effect of design and operating parameters on the performance of the heat pipe has been studied. The variations in contact angle have been found to significantly affect the performance of a micro heat pipe. The performance of a micro heat pipe is susceptible to ungrooved area of a V-shaped micro heat pipe. If the groove is not sharp enough i.e., the radius of ungrooved substrate is more; the micro heat pipe may cease to work even before it reaches its other operating limits. The various sensitivity studies made in this work gives better understanding of variations in thermophysical properties and design parameters of a micro heat pipe. © 2005 Elsevier Ltd. All rights reserved.