This paper investigates the production of stable nanoparticle suspensions. The experimental set-up allows the online measurement of the most important electrochemical properties and the particle size distribution of the product suspension as well as an adjustment of the pH-value for stabilization during the comminution process. Electrostatic stabilization is a strong tool to produce stable nanoparticle suspensions for sparingly soluble oxide components. In this contribution the influence of different operational parameters at stable suspensions properties on the grinding result in the nanometer size range is presented. In addition to alumina, the concept of electrostatic stabilization during wet grinding of nanoparticles is also applied to tin oxide. (c) 2005 Elsevier Ltd. All rights reserved.