The activity of Au/C catalysts has been reviewed in the liquid phase oxidation of alcohols as a function of preparation method, particle size and dispersion, surface exposure and nature of the support. A strong influence of substrate structure has also been observed. Monometallic Au on carbon catalysts show a unique behaviour in the liquid phase oxidation of alcohols compared with Pt- and Pd-based systems, characterised by a higher resistance to poisoning from both oxygen and (by)products normally affecting other catalysts. (c) 2005 Elsevier B.V. All rights reserved.