This paper presents an analysis using computational and scaling methods of pulsatile capillary Poiseuille flow of a model anisotropic viscoelastic discotic liquid crystalline material. The analysis shows that pulsatile pressure drops applied to anisotropic materials can result in flow-rate enhancement or reduction, defined as the relative flow-rate change with respect to the steady-state flow rate, for a given average pressure drop, amplitude, and frequency. It is found that flow-rate modification in pulsatile flow is a direct result of orientation-dependent viscosity. The role of average pressure drop, oscillation amplitude, and frequency on flow enhancement is characterized and explained. The new mechanism of flow-enhancement in liquid crystals subjected to pulsatile pressure is expected to be useful to the fundamental understanding of pulsatile flows of anisotropic suspensions and anisotropic biological fluids. (c) 2005 Elsevier Ltd. All rights reserved.