We show that when poly(ethylene glycol) (PEG) is dissolved in isobutyric acid at temperatures below about 55 degrees C, the polymer molecule can form helices. Small-angle neutron scattering indicates that in pure isobutyric acid and in isobutyric acid-rich aqueous solutions the polymer chains form stiff rods that coexist with polymer coils when the polymer molecular weight is 2.38 x 10(4), 2.13 x 10(5), and 2.87 x 10(5) g/mol, but that at the lower molecular weight of 1.73 x 10(2), only the polymer rods form. The addition of chiral dopants causes a net optical rotation in the solution, indicating that the rods are actually helices. Above about 60 degrees C in deuterated isobutyric acid (and above about 70 degrees C in hydrogenated isobutyric acid), the helices convert to coils. In water, the PEG molecules form coils which persist over the entire temperature range studied (25-60 degrees C).