Journal of the American Chemical Society, Vol.127, No.45, 15744-15748, 2005
Slow diffusion by singlet state NMR spectroscopy
Small diffusion coefficients can be measured by using populations of singlet states that have a relaxation time constant, T-s, which can be much longer than the longitudinal relaxation time, T-1. Spatial information can be encoded with pulsed field gradients in the manner of stimulated echo sequences. Singlet states can be excited via double-quantum coherences to enhance the efficiency of phase encoding and decoding.