고주파 자계 온열요법 연구를 위한 젤리형의 고분자계 모의인체

김오영; 최창영; 마승재; 임상명; 서기택; Ohyoung Kim; Chang Young Choi; Sung Jae Ma; Sang Mung Lim; Kitaek Seo

Polymer(Korea), Vol.30, No.6, 572-575, November, 2006

Development of Jelly-Type Simulating Polymer Based Human Tissue for Research on Hyperthermia by High Frequency Magnetic Field

김오영 ^†, 최창영, 마승재, 임상명, 서기택

단국대학교 공과대학 고분자공학전공

Ohyoung Kim^†, Chang Young Choi, Sung Jae Ma, Sang Mung Lim, and Kitaek Seo

Department of Polymer Science & Engineering, Dankook University, Seoul 140-714, Korea

E-mail:

초록

사회적 관심이 되고 있는 전력선과 휴대폰의 전자파 영향에 의한 인체 유해성 문제에 대한 상대적 개념으로 암 치료에 있어서 보조요법의 일환으로 제시될 수 있는 전자파를 이용한 온열치료법 개발을 위한 기초연구로서 고분자계의 젤리팬텀을 제작하였다. 폴리에틸렌을 비롯한 다양한 구성비를 가지는 팬텀 재료의 조합을 통해 CDMA와 PCS 대역에 적용되는 인체 두뇌의 젤리팬텀을 제작한 후 전기적 특성을 분석하였다. 본 연구는 향후 제조된 젤리팬텀을 비롯한 각종 장기의 모의인체에 대한 전기적 특성 값을 분석한 다음, 자성유체를 젤리팬텀에 주입시킨 후 실제 온도상승을 온도감지 적외선 카메라로 촬영하여 확인, 젤리팬텀의 전자기적 특성 분석을 통한 암 치료에 있어서의 새로운 방법론을 제시할 수 있을 것으로 기대된다.

In this work, a variety of polymer based jelly phantoms suitable for the hyperthermia operations to human organs was synthesized in order to confirm the possibility of auxiliary cancer therapy. Specifically, using an appropriate material composition including polyethylene, jelly phantoms for brain was prepared and characterized their electrical properties suitable for the monitoring the effect of electromagnetic wave from code division multiple access (CDMA) and personal communication service (PCS) on the human body. In the future, after injection of ferromagnetic nanoparticle into the jelly phantoms, new approach to propose the cancer therapy can be anticipated by monitoring the degree of temperature rise in human body using the photograph of infrared camera.

Keywords:hyperthermia;CDMA;PCS;jelly phantom;polyethylene

[References]

ICNIRP Guideline(Guidelines For Limiting Exposure to Time-Varying Electric. Magnetic. and Electromagnetic Fields(up to 300 GHz), International Commission on Non-Ionizing Radiation Protection
Koichi I, Hiroki K, Kazuyuki S, IEICE, J85-B, 582 (2002)
Yoshinobu O, Koichi I, Ichirou I, Masaharu T, IEEE Transaction on microwave theory and techniques, 48, Nov (2000)
NANOBIOTECH NEWS, 3, July 13 (2005)
Ito A, Kuga Y, Honda H, Kikkawa H, Horiuchi A, Watanabe Y, Kobayashi T, Cancer Lett., 212, 167 (2004)
Gao Y, "Biofunctionalization of magnetic nanoparticles", in Nanotechnologies for the life sciences, Challa S. S. R. Kumar, Editors, Wiley-VCH, Vol 1, p. 72 (2005)
Gimm YM, Kim JH, The 4th International Conference on Electromagnetic Fields and Biological Effects, Ministry of Health China, pp. 36-37, Sept (2005)
Durney CH, Massouni H, Iskander MF, Radiofrequency radiation dosimetry handbook, 4th ed., Chap. 3, The Univ. of Utah, Utah (1986)

[Referenced By]

[Related Articles]

[1] ICNIRP Guideline(Guidelines For Limiting Exposure to Time-Varying Electric. Magnetic. and Electromagnetic Fields(up to 300 GHz), International Commission on Non-Ionizing Radiation Protection

[2] Koichi I, Hiroki K, Kazuyuki S, IEICE, J85-B, 582 (2002)

[3] Yoshinobu O, Koichi I, Ichirou I, Masaharu T, IEEE Transaction on microwave theory and techniques, 48, Nov (2000)

[4] NANOBIOTECH NEWS, 3, July 13 (2005)

[5] Ito A, Kuga Y, Honda H, Kikkawa H, Horiuchi A, Watanabe Y, Kobayashi T, Cancer Lett., 212, 167 (2004)

[6] Gao Y, "Biofunctionalization of magnetic nanoparticles", in Nanotechnologies for the life sciences, Challa S. S. R. Kumar, Editors, Wiley-VCH, Vol 1, p. 72 (2005)

[7] Gimm YM, Kim JH, The 4th International Conference on Electromagnetic Fields and Biological Effects, Ministry of Health China, pp. 36-37, Sept (2005)

[8] Durney CH, Massouni H, Iskander MF, Radiofrequency radiation dosimetry handbook, 4th ed., Chap. 3, The Univ. of Utah, Utah (1986)