A comprehensive and chronological account of dendrimers based on [1,3,5]-triazines is provided. Synthetic strategies to install the triazine through cycloaddition, cyclotrimerization, and nucleophilic aromatic substitution of cyanuric chloride are discussed. Motivations and applications of these architectures are surveyed, including the preparation of supramolecular assemblies in the solution and solid states and their use in medicines, advanced materials, and separations when anchored to solid supports. (D 2006 Wiley Periodicals, Inc.