Wall pressure fluctuations were measured in bubble columns at different locations and for different gas velocities and height to diameter ratios. Non-linear analysis of the acquired data of pressure fluctuations was carried out to quantify dynamic characteristics. A bubble-bubble interaction model was developed to simulate voidage fluctuations in bubble columns. Dynamic characteristics of the simulated voidage fluctuations were compared with those of measured pressure fluctuations. The data and analysis will be useful to validate full transient CFD simulations of gas-liquid flow in bubble columns.