Journal of Bioscience and Bioengineering, Vol.101, No.6, 511-514, 2006
Activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen scaffold
We investigated the effect of gamma-irradiation on the activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen (SAC) scaffolds. SAC-cultured samples were irradiated at doses of 10, 15, and 25 kGy. gamma-Irradiation had a significant impact on the activities of MC3T3-E1 cells. The proliferation rates and alkaline phosphatase activities of MC3T3-E1 cells increased with gamma-irradiation dose.
Keywords:gamma-irradiation;salmon atelocollagen;MC3T3-E1 cells;proliferation rate;alkaline phosphatase activity