Oxidation activity and stability under reaction was investigated for a series of mixed oxide catalysts, doped or not by a precious metal (Pd, Pt). The reaction feedstock, containing CO, H-2, CH4, CO2 and H2O, simulated gases issued from H-2 production processes for fuel cells. Contrarily to conventional noble metal catalysts, mixed oxide samples present generally good stability under reaction at high temperature. The activities measured for the perovskite and hexaaluminate catalysts, are however largely lower than that of the reference Pd/Al2O3 catalyst. High activities were obtained after impregnation of 1.1 wt. % Pd or 0.8 wt. % Pt on the hexaaluminates samples. Even if Pd/Al2O3 was found to present a high activity, this sample suffered from drastic deactivation at 700 degrees C. Better stability were obtained on perovskite. Furthermore, doping hexaaluminate by Pt led to samples with good activities and high stability. Even if better activities were obtained by doping the hexaaluminate samples by Pd, the Pd/BaAl12O19 strongly deactivated, as it was previously observed for the reference catalyst. Interestingly, this Pd deactivation was not observed when Pd was impregnated on the Mn substituted hexaaluminate, leading to a stable and active catalyst. This suggests that it is possible to stabilize the palladium in its oxidized form at high temperature (700 degrees C) on the surface of some supports. (c) 2006 Elsevier B.V. All rights reserved.