A model is proposed to account for the interaction energy and adhesion force between petroleum asphaltenes and metallic surfaces. It is assumed that the total molecule-surface interaction potential may be constructed through superposition of corresponding interactions with a relevant number of atomic layers forming the substrate and resorting to the Lindhard continuum planar potential (CPP) approximation, which requires only of knowledge of binary molecule-atom interactions. Molecular mechanics (MM) calculations are performed to generate the average binary interaction between the asphaltene molecule and an atom in the substrate, which in turn is represented by a parameterized analytical-physically sound-expression. The resulting CPP yields an analytical expression representing the interaction between the asphaltene molecule and each substrate layer. To validate the method, pilot calculations are performed for a sample asphaltene molecule with a fixed orientation relative to metallic surfaces of iron, aluminum, and chromium. Comparison between corresponding CPP and MM calculations for the asphaltene-plane (A-P) and asphaltene-substrate (A-S) interactions indicate reasonable agreement pointing to the adequacy of the CPP method to represent molecule-surface interactions. Also, the effect of a surrounding (i.e., solvent) medium is addressed with the use of a dielectric constant, E, incorporated in the molecule-atom potential. Finally, a discussion is presented on the applicability of the method to generate an analytical universal expression for asphaltene-metallic wall interactions. (c) 2006 Published by Elsevier Inc.