The dynamics of polymeric liquids and mixtures spreading on a solid surface have been investigated on completely wetting and partially wetting surfaces. Drops were formed by pushing the test liquid through a hole in the underside of the substrate, and the drop profiles were monitored as the liquid wet the surface. Silicon surfaces coated with diphenyldichlorosilane (DPDCS) and octadecyltrichlorosilane (OTS) were used as wetting and partial wetting surfaces, respectively, for the fluids we investigated. The response under complete and partial wetting conditions for a series of polypropylene glycols (PPG) with different molecular weights and the same surface tension could be collapsed onto a single curve when scaling time based on the fluid viscosity, the liquid-vapor surface tension, and the radius of a spherical drop with equivalent volume. A poly(ethylene glycol) (PEG300) and a series of poly(ethylene oxide-rand-propylene oxide) copolymers did not show the same viscosity scaling when spread on the partially wetting surface. A combined model incorporating hydrodynamic and molecular-kinetic wetting models adequately described the complete wetting results. The assumptions in the hydrodynamic model, however, were not valid under the partial wetting conditions in our work, and the molecular-kinetic model was chosen to describe our results. The friction coefficient used in the molecular-kinetic model exhibited a nonlinear dependence with viscosity for the copolymers, indicating a more complex relationship between the friction coefficient and the fluid viscosity.