In this study, a series of self-crosslinked acrylic rubbers were prepared by gamma ray initiated emulsion copolymerization. Acrylic acid and N-hydroxymethl acrylamide were used as the cure-site monomers. The vulcanizing properties, tensile properties, and dynamic mechanical analysis of the self-crosslinked acrylic rubbers were investigated. It was found that the curing characteristics could be influenced significantly by the content and species of the cure-site monomers. Improvement in mechanical properties like tensile strength, modulus and elongation at break was observed in the prepared self-crosslinked rubber. The structure-property correlation of the self-crosslinked acrylic rubber was discussed.