Chemical Reviews, Vol.97, No.7, 2611-2629, 1997
Biosynthesis of Erythromycin and Rapamycin
Keywords:MODULAR POLYKETIDE SYNTHASE;FATTY-ACID SYNTHASE;ASYMMETRIC TOTAL SYNTHESIS;SACCHAROPOLYSPORA-ERYTHRAEA;STREPTOMYCES-HYGROSCOPICUS;ENGINEERED BIOSYNTHESIS;MACROLIDE BIOSYNTHESIS;SUBSTRATE-SPECIFICITY;CHAIN-ELONGATION;GENE-CLUSTER