The activity of molybdenum and tungsten carbides in hydrodenitrogenation (HDN) of carbazole was studied. Transition metal carbides (Mo2C and W,C) were synthesized using the temperature-programmed reaction of the appropriate oxide precursor (MoO3 and WO3) with the following gas mixture: 10 vol.% CH4/H-2. The structure of the catalysts was characterized using X-ray diffraction, CO chemisorption, high resolution transmission electron microscopy (HRTEM) and BET surface area measurements. From the HRTEM analysis, it could be concluded that the tungsten carbide was thioresistant in our operating conditions (50 ppm of S, pressure = 6 MPa, 553 < T < 653 K, H-2/feed volumic ratio 600). In the case Of Mo2C, molybdenum sulphide was observed as single slabs. The activity of catalysts was determined during the hydroodenitrogenation of carbazole at the wide range of temperature (553-653 K) and under a 6 MPa total pressure of H-2. The comparison of tungsten carbide and molybdenum carbide has shown higher activity of Mo2C than W2C at the same condition. However, W2C leads to higher amount of isomers of main products, and have higher hydrogenation activity. (c) 2006 Elsevier B.V. All fights reserved.