A silver complex is transformed into amphiphilic nanoparticles at room temperature using nanoreactors formed from an amphiphilic polyester. It takes a few minutes to form silver nanocolloids with a narrow particle size distribution. Developed silver forms a stable dispersion in both polar and nonpolar media. The amphiphilic polyester acts as a reducing and stabilizing agent simultaneously. The size of the synthesized amphiphilic silver nanoparticles depends on the concentration of the invertible polyester and solvent polarity.